Age-Related Effects of Exogenous Melatonin on Anxiety-like Behavior in C57/B6J Mice

The synthesis of melatonin (MLT) physiologically decreases during aging. Treatment with MLT has shown anxiolytic, hypnotic, and analgesic effects, but little is known about possible age-dependent differences in its efficacy. Therefore, we studied the effects of MLT (20 mg/kg, intraperitoneal) on anx...

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Bibliographic Details
Main Authors: Sofia Nasini, Sara Tidei, Atea Shkodra, Danilo De Gregorio, Marco Cambiaghi, Stefano Comai
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Biomedicines
Subjects:
Online Access:https://www.mdpi.com/2227-9059/11/6/1705