Discrimination of Head and Neck Squamous Cell Carcinoma Patients and Healthy Adults by 10-Color Flow Cytometry: Development of a Score Based on Leukocyte Subsets

Discrimination of Head and Neck Squamous Cell Carcinoma Patients and Healthy Adults by 10-Color Flow Cytometry: Development of a Score Based on Leukocyte Subsets

Background: Leukocytes in peripheral blood (PB) are prognostic biomarkers in head and neck squamous cell carcinoma cancer patients (HNSCC-CPs), but differences between HNSCC-CPs and healthy adults (HAs) are insufficiently described. Methods: 10-color flow cytometry (FCM) was used for in-depth immuno...

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Bibliographic Details
Main Authors: Gunnar Wichmann, Clara Gaede, Susanne Melzer, Jozsef Bocsi, Sylvia Henger, Christoph Engel, Kerstin Wirkner, John Ross Wenning, Theresa Wald, Josefine Freitag, Maria Willner, Marlen Kolb, Susanne Wiegand, Markus Löffler, Andreas Dietz, Attila Tárnok
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Cancers
Subjects:
head and neck squamous cell carcinoma (HNSCC)
multicolor flow cytometry
peripheral blood
leukocyte subsets
cancer biomarker
predictive value
monocytes-to-lymphocytes ratio (MLR)
monocytes-to-granulocytes ratio (MGR)
classical monocytes
propensity score matching
Online Access:https://www.mdpi.com/2072-6694/11/6/814

Internet

https://www.mdpi.com/2072-6694/11/6/814

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