Nile Tilapia Derived Antimicrobial Peptide TP4 Exerts Antineoplastic Activity Through Microtubule Disruption

Some antimicrobial peptides (AMPs) exhibit anti-cancer activity, acting on cancer cells either by causing membrane lysis or via intracellular effects. While intracellular penetration of AMPs has been shown to cause cancer cell death, the mechanisms of toxicity remain largely unknown. Here we show th...

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Bibliographic Details
Main Authors: Chen-Hung Ting, Yi-Chung Liu, Ping-Chiang Lyu, Jyh-Yih Chen
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:Marine Drugs
Subjects:
Online Access:https://www.mdpi.com/1660-3397/16/12/462