The Pathogenesis in Alzheimer's Disease: TREM2 as a Potential Target

Alzheimer’s disease (AD) is ranked as the third-most expensive illness and sixth leading cause of mortality. It is associated with the deposition of extracellular amyloid-β (Aβ) in neural plaques (NPs), as well as intracellular hyperphosphorylated tau proteins that form neurofibrillary tangles (NFTs...

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Bibliographic Details
Main Authors: Guangtong Liu, Linlin Zhang, Yongzhao Fan, Wenliang Ji
Format: Article
Language:English
Published: IMR Press 2023-10-01
Series:Journal of Integrative Neuroscience
Subjects:
Online Access:https://www.imrpress.com/journal/JIN/22/6/10.31083/j.jin2206150