Evaluation of the Effects of Heteroaryl Ethylene Molecules in Combination with Antibiotics: A Preliminary Study on Control Strains

Evaluation of the Effects of Heteroaryl Ethylene Molecules in Combination with Antibiotics: A Preliminary Study on Control Strains

The discovery of compounds with antibacterial activity is crucial in the ongoing battle against antibiotic resistance. We developed two QSAR models to design six novel heteroaryl drug candidates and assessed their antibacterial properties against nine ATCC strains, including <i>Enterococcus fa...

Full description

Bibliographic Details
Main Authors: Carmelo Bonomo, Paolo Giuseppe Bonacci, Dalida Angela Bivona, Alessia Mirabile, Dafne Bongiorno, Emanuele Nicitra, Andrea Marino, Carmela Bonaccorso, Giuseppe Consiglio, Cosimo Gianluca Fortuna, Stefania Stefani, Nicolò Musso
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Antibiotics
Subjects:
antimicrobial resistant
heteroaryl ethylene derivatives
QSAR model
antibiotics
antitumor compounds
combination therapy
Online Access:https://www.mdpi.com/2079-6382/12/8/1308

Internet

https://www.mdpi.com/2079-6382/12/8/1308

Similar Items