Randomized Clinical and Biochemical Study Comparing the Effect of L-arginine and Sildenafil in Beta Thalassemia Major Children With High Tricuspid Regurgitant Jet Velocity

Background: Pulmonary hypertension (PHT) is common in β-thalassemia patients due to hemolysis, iron overload and diminished nitric oxide (NO) levels. Biochemical markers can help to understand the pathophysiology and to introduce new therapies for this condition. Aim: This study aimed to evaluate th...

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Bibliographic Details
Main Authors: Eman El-Khateeb PhD, Sahar Mohamed El-Haggar PhD, Osama El-Razaky MD, Mohamed Ramadan El-Shanshory MD, Tarek Mohamed Mostafa PhD
Format: Article
Language:English
Published: SAGE Publishing 2022-10-01
Series:Journal of Cardiovascular Pharmacology and Therapeutics
Online Access:https://doi.org/10.1177/10742484221132671