Simulation of E. coli gene regulation including overlapping cell cycles, growth, division, time delays and noise.

Due to the complexity of biological systems, simulation of biological networks is necessary but sometimes complicated. The classic stochastic simulation algorithm (SSA) by Gillespie and its modified versions are widely used to simulate the stochastic dynamics of biochemical reaction systems. However...

Full description

Bibliographic Details
Main Authors: Ruoyu Luo, Lin Ye, Chenyang Tao, Kankan Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3637171?pdf=render