Recent advances of sorafenib nanoformulations for cancer therapy: Smart nanosystem and combination therapy

Sorafenib, a molecular targeted multi-kinase inhibitor, has received considerable interests in recent years due to its significant profiles of efficacy in cancer therapy. However, poor pharmacokinetic properties such as limited water solubility, rapid elimination and metabolism lead to low bioavaila...

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Bibliographic Details
Main Authors: Fangmin Chen, Yifan Fang, Xiang Chen, Rui Deng, Yongjie Zhang, Jingwei Shao
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:Asian Journal of Pharmaceutical Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1818087620303494