Employing synthetic biology to expand antibiotic discovery

Employing synthetic biology to expand antibiotic discovery

Antimicrobial-resistant (AMR) bacterial pathogens are a continually growing threat as our methods for combating these infections continue to be overcome by the evolution of resistance mechanisms. Recent therapeutic methods have not staved off the concern of AMR infections, so continued research focu...

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Bibliographic Details
Main Authors: Greta D. Cook, Nikolas M. Stasulli
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:SLAS Technology
Subjects:
Synthetic biology
Biosynthetic gene cluster (BGC)
Cryptic BGCs
Natural products (NPs)
Mutagenesis
Endogenous gene expression
Online Access:http://www.sciencedirect.com/science/article/pii/S2472630324000025

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http://www.sciencedirect.com/science/article/pii/S2472630324000025

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