Optogenetic stimulation of VTA dopamine neurons reveals that tonic but not phasic patterns of dopamine transmission reduce ethanol self-administration

Optogenetic stimulation of VTA dopamine neurons reveals that tonic but not phasic patterns of dopamine transmission reduce ethanol self-administration

There is compelling evidence that acute ethanol exposure stimulates ventral tegmental area (VTA) dopamine cell activity and that VTA-dependent dopamine release in terminal fields within the nucleus accumbens plays an integral role in the regulation of ethanol drinking behaviors. Unfortunately, due...

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Bibliographic Details
Main Authors: Caroline E Bass, Valentina P Grinevich, Dominic eGioia, Jon eDay-Brown, Keith D Bonin, Garret D Stuber, Jeff L Weiner, Evgeny eBudygin
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-11-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Dopamine
Nucleus Accumbens
optogenetics
VTA
ethanol self-administration
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2013.00173/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnbeh.2013.00173/full

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