Cerebral Iron Deposition in Neurodegeneration

Disruption of cerebral iron regulation appears to have a role in aging and in the pathogenesis of various neurodegenerative disorders. Possible unfavorable impacts of iron accumulation include reactive oxygen species generation, induction of ferroptosis, and acceleration of inflammatory changes. Who...

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Bibliographic Details
Main Authors: Petr Dusek, Tim Hofer, Jan Alexander, Per M. Roos, Jan O. Aaseth
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/12/5/714