SNORA23 inhibits HCC tumorigenesis by impairing the 2′-O-ribose methylation level of 28S rRNA

SNORA23 inhibits HCC tumorigenesis by impairing the 2′-O-ribose methylation level of 28S rRNA

Objective: The dysregulation of ribosome biogenesis is associated with the progression of numerous tumors, including hepatocellular carcinoma (HCC). Small nucleolar RNAs (snoRNAs) regulate ribosome biogenesis by guiding the modification of ribosomal RNAs (rRNAs). However, the underlying mechanism of...

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Bibliographic Details
Main Authors: Zhiyong Liu, Yanan Pang, Yin Jia, Qin Qin, Rui Wang, Wei Li, Jie Jing, Haidong Liu, Shanrong Liu
Format: Article
Language:English
Published: China Anti-Cancer Association 2022-01-01
Series:Cancer Biology & Medicine
Subjects:
snora23
ribosome biogenesis
rrna methylation
hcc
Online Access:http://www.cancerbiomed.org/index.php/cocr/article/view/1818

Internet

http://www.cancerbiomed.org/index.php/cocr/article/view/1818

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