Silicone oil-induced ocular hypertension and glaucomatous neurodegeneration in mouse

Silicone oil-induced ocular hypertension and glaucomatous neurodegeneration in mouse

Understanding the molecular mechanism of glaucoma and development of neuroprotectants is significantly hindered by the lack of a reliable animal model that accurately recapitulates human glaucoma. Here, we sought to develop a mouse model for the secondary glaucoma that is often observed in humans af...

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Bibliographic Details
Main Authors: Jie Zhang, Liang Li, Haoliang Huang, Fang Fang, Hannah C Webber, Pei Zhuang, Liang Liu, Roopa Dalal, Peter H Tang, Vinit B Mahajan, Yang Sun, Shaohua Li, Mingchang Zhang, Jeffrey L Goldberg, Yang Hu
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-05-01
Series:eLife
Subjects:
glaucoma
retinal ganglion cell
optic nerve
neurodegeneration
intraocular pressure
neuroprotection
Online Access:https://elifesciences.org/articles/45881

Internet

https://elifesciences.org/articles/45881

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