Next-Generation Sequencing in Oncology: Genetic Diagnosis, Risk Prediction and Cancer Classification

Next-Generation Sequencing in Oncology: Genetic Diagnosis, Risk Prediction and Cancer Classification

Next-generation sequencing (NGS) technology has expanded in the last decades with significant improvements in the reliability, sequencing chemistry, pipeline analyses, data interpretation and costs. Such advances make the use of NGS feasible in clinical practice today. This review describes the rece...

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Bibliographic Details
Main Authors: Rick Kamps, Rita D. Brandão, Bianca J. van den Bosch, Aimee D. C. Paulussen, Sofia Xanthoulea, Marinus J. Blok, Andrea Romano
Format: Article
Language:English
Published: MDPI AG 2017-01-01
Series:International Journal of Molecular Sciences
Subjects:
next-generation sequencing
whole-exome-sequencing
whole-genome-sequencing
gene-panel
inherited cancer syndrome
cancer somatic mutation
diagnostics
genetic modifiers
theranostics
Online Access:http://www.mdpi.com/1422-0067/18/2/308

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http://www.mdpi.com/1422-0067/18/2/308

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