Different Methods for Evaluating Microglial Activation Using Anti-Ionized Calcium-Binding Adaptor Protein-1 Immunohistochemistry in the Cuprizone Model

Different Methods for Evaluating Microglial Activation Using Anti-Ionized Calcium-Binding Adaptor Protein-1 Immunohistochemistry in the Cuprizone Model

Microglia play an important role in the pathology of various central nervous system disorders, including multiple sclerosis (MS). While different methods exist to evaluate the extent of microglia activation, comparative studies investigating the sensitivity of these methods are missing for most mode...

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Bibliographic Details
Main Authors: Mariela Wittekindt, Hannes Kaddatz, Sarah Joost, Anna Staffeld, Yamen Bitar, Markus Kipp, Linda Frintrop
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Cells
Subjects:
microglia
multiple sclerosis
IBA1
cuprizone model
Online Access:https://www.mdpi.com/2073-4409/11/11/1723

Internet

https://www.mdpi.com/2073-4409/11/11/1723

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