Plasmacytoid dendritic cells are increased in cerebrospinal fluid of untreated patients during multiple sclerosis relapse

<p>Abstract</p> <p>The plasmacytoid dendritic cells (pDCs) express a high level of Toll-like receptor 9 (TLR-9), which recognizes viral DNA. Activated via TLR-9, pDCs also secrete large amounts of type I interferon which are involved either in stimulation or down regulation of immu...

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Main Authors: Quispe-Cabanillas Juan G, Oliveira Elaine C, Farias Alessandro S, Moraes Adriel S, Pradella Fernando, de Paula Rosemeire FO, Brandão Carlos, von Glehn Felipe, Longhini Ana, Abreu Cassiana, Damasceno Alfredo, Damasceno Benito P, Balashov Konstantin E, Santos Leonilda MB
Format: Article
Language:English
Published: BMC 2011-01-01
Series:Journal of Neuroinflammation
Online Access:http://www.jneuroinflammation.com/content/8/1/2