Clinical Uses of Botulinum Neurotoxins: Current Indications, Limitations and Future Developments
Botulinum neurotoxins (BoNTs) cause flaccid paralysis by interfering with vesicle fusion and neurotransmitter release in the neuronal cells. BoNTs are the most widely used therapeutic proteins. BoNT/A was approved by the U.S. FDA to treat strabismus, blepharospam, and hemificial spasm as early as 19...
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| Format: | Article |
| Language: | English |
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MDPI AG
2012-10-01
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| Series: | Toxins |
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| Online Access: | http://www.mdpi.com/2072-6651/4/10/913 |