NSG Mice Provide a Better Spontaneous Model of Breast Cancer Metastasis than Athymic (Nude) Mice.

Metastasis is the most common cause of mortality in breast cancer patients worldwide. To identify improved mouse models for breast cancer growth and spontaneous metastasis, we examined growth and metastasis of both estrogen receptor positive (T47D) and negative (MDA-MB-231, SUM1315, and CN34BrM) hum...

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Bibliographic Details
Main Authors: Madhavi Puchalapalli, Xianke Zeng, Liang Mu, Aubree Anderson, Laura Hix Glickman, Ming Zhang, Megan R Sayyad, Sierra Mosticone Wangensteen, Charles V Clevenger, Jennifer E Koblinski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5035017?pdf=render