RPS6KA5 methylation predict response to 6-week treatment for adolescent MDD patients

RPS6KA5 methylation predict response to 6-week treatment for adolescent MDD patients

Abstract Objective We aimed to investigate the effect of differentially methylated genes and chronic childhood stress on the development of depressive symptoms in Chinese adolescents, as well as to test whether methylation at baseline can be used as a predictor of remission at follow-up after six we...

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Bibliographic Details
Main Authors: Peiwei Xu, Yuanmei Tao, Hang Zhang, Meijiang Jin, Hanmei Xu, Shoukang Zou, Fang Deng, Lijuan Huang, Hong Zhang, Xiaolan Wang, Xiaowei Tang, Zaiquan Dong, Yanping Wang, Li Yin, Xueli Sun
Format: Article
Language:English
Published: BMC 2022-08-01
Series:BMC Psychiatry
Subjects:
Major depressive disorder
Adolescent
Chronic childhood stress
DNA methylation
Treatment response
Online Access:https://doi.org/10.1186/s12888-022-04196-4

Internet

https://doi.org/10.1186/s12888-022-04196-4

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