Therapeutic Application of Extracellular Vesicles-Capsulated Adeno-Associated Virus Vector via <i>nSMase2/Smpd3</i>, Satellite, and Immune Cells in Duchenne Muscular Dystrophy
Duchenne muscular dystrophy (DMD) is caused by loss-of-function mutations in the dystrophin gene on chromosome Xp21. Disruption of the dystrophin–glycoprotein complex (DGC) on the cell membrane causes cytosolic Ca<sup>2+</sup> influx, resulting in protease activation, mitochondrial dysfu...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-01-01
|
| Series: | International Journal of Molecular Sciences |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1422-0067/23/3/1551 |