Enhanced Aggression, Reduced Self-Grooming Behavior and Altered 5-HT Regulation in the Frontal Cortex in Mice Lacking Trace Amine-Associated Receptor 1 (TAAR1)

Enhanced Aggression, Reduced Self-Grooming Behavior and Altered 5-HT Regulation in the Frontal Cortex in Mice Lacking Trace Amine-Associated Receptor 1 (TAAR1)

The Trace Amine-Associated Receptor 1 (TAAR1) is one of the six functional receptors belonging to the family of monoamine-related G protein-coupled receptors (TAAR1-TAAR9) found in humans. However, the exact biological mechanisms of TAAR1 central and peripheral action remain to be fully understood....

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Bibliographic Details
Main Authors: Ilya S. Zhukov, Inessa V. Karpova, Nataliya A. Krotova, Ilya Y. Tissen, Konstantin A. Demin, Petr D. Shabanov, Evgeny A. Budygin, Allan V. Kalueff, Raul R. Gainetdinov
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:International Journal of Molecular Sciences
Subjects:
TAAR1
gene knockout
aggression
grooming
serotonin
frontal cortex
Online Access:https://www.mdpi.com/1422-0067/23/22/14066

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https://www.mdpi.com/1422-0067/23/22/14066

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