Induction of BVR-A Expression by Korean Red Ginseng in Murine Hippocampal Astrocytes: Role of Bilirubin in Mitochondrial Function via the LKB1–SIRT1–ERRα Axis

Induction of BVR-A Expression by Korean Red Ginseng in Murine Hippocampal Astrocytes: Role of Bilirubin in Mitochondrial Function via the LKB1–SIRT1–ERRα Axis

The beneficial effects of Korean red ginseng extract (KRGE) on the central nervous system (CNS) have been reported. Among the CNS cells, astrocytes possess robust antioxidative properties and regenerative potential. Under physiological conditions, biliverdin reductase A (BVR-A) converts biliverdin (...

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Bibliographic Details
Main Authors: Sunhong Moon, Chang-Hee Kim, Jinhong Park, Minsu Kim, Hui Su Jeon, Young-Myeong Kim, Yoon Kyung Choi
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Antioxidants
Subjects:
liver kinase B1
biliverdin reductase
antioxidants
bilirubin
mitochondrial membrane potential
oxidative phosphorylation
Online Access:https://www.mdpi.com/2076-3921/11/9/1742

Internet

https://www.mdpi.com/2076-3921/11/9/1742

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