Multi-tissue and multi-scale approach for nuclei segmentation in H&E stained images

Abstract Background Accurate nuclei detection and segmentation in histological images is essential for many clinical purposes. While manual annotations are time-consuming and operator-dependent, full automated segmentation remains a challenging task due to the high variability of cells intensity, si...

Full description

Bibliographic Details
Main Authors: Massimo Salvi, Filippo Molinari
Format: Article
Language:English
Published: BMC 2018-06-01
Series:BioMedical Engineering OnLine
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12938-018-0518-0