Evaluation and Optimization of Microdrop Digital PCR for Detection of Serotype A and B Clostridium botulinum

Evaluation and Optimization of Microdrop Digital PCR for Detection of Serotype A and B Clostridium botulinum

Clostridium botulinum is the causative pathogen of botulism. Laboratory detection of C. botulinum is essential for clinical therapy treatment of botulism due to the difficulty in diagnosis, especially in infant botulism. The extreme toxicity of botulinum neurotoxin (BoNT) requires a sensitive detect...

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Bibliographic Details
Main Authors: Pengya Gao, Changde Wu, Jin Zhang, Shuping Wang, Ying Huang, Yinping Dong, Tingting Liu, Changyun Ye, Xuefang Xu, Wenwen Xin
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Microbiology
Subjects:
Clostridium botulinum
droplet digital PCR
rapid clinical diagnosis
neurotoxin
q-PCR
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.860992/full

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https://www.frontiersin.org/articles/10.3389/fmicb.2022.860992/full

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