Brain Cholesterol Biosynthetic Pathway Is Altered in a Preclinical Model of Fragile X Syndrome

Brain Cholesterol Biosynthetic Pathway Is Altered in a Preclinical Model of Fragile X Syndrome

Fragile X Syndrome (FXS) is the most frequent form of inherited X-linked pathology, associated with an intellectual and developmental disability, and currently considered the first monogenic cause of autism spectrum disorder (ASD). Low levels of total cholesterol reported in the serum of FXS patient...

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Bibliographic Details
Main Authors: Martina Parente, Claudia Tonini, Valeria Buzzelli, Emilia Carbone, Viviana Trezza, Valentina Pallottini
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:International Journal of Molecular Sciences
Subjects:
3-Hydroxy 3-methylglutaryl Coenzyme A reductase
brain
cholesterol
<i>Fmr1-Δexon 8</i> rat
Fragile X Syndrome
low-density lipoprotein receptor
Online Access:https://www.mdpi.com/1422-0067/23/6/3408

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https://www.mdpi.com/1422-0067/23/6/3408

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