CHIP protects against septic acute kidney injury by inhibiting NLRP3-mediated pyroptosis

CHIP protects against septic acute kidney injury by inhibiting NLRP3-mediated pyroptosis

Summary: Septic acute kidney injury (S-AKI), the most common type of acute kidney injury (AKI), is intimately related to pyroptosis and oxidative stress in its pathogenesis. Carboxy-terminus of Hsc70-interacting protein (CHIP), a U-box E3 ligase, modulates oxidative stress by degrading its targeted...

Full description

Bibliographic Details
Main Authors: Hao Zhang, Zebin Deng, Yilong Wang, Xiaoping Zheng, Lizhi Zhou, Shu Yan, Yinhuai Wang, Yingbo Dai, Yashpal.S. Kanwar, Fei Deng
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:iScience
Subjects:
Nephrology
Molecular physiology
Molecular medicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223018394

Internet

http://www.sciencedirect.com/science/article/pii/S2589004223018394

Similar Items