Antidepressive-like Behavior-Related Metabolomic Signatures of Sigma-1 Receptor Knockout Mice

Sigma-1 receptor (Sig1R) has been proposed as a therapeutic target for neurological, neurodegenerative, and psychiatric disorders, including depression and anxiety. Identifying metabolites that are affected by Sig1R absence and cross-referencing them with specific mood-related behaviors would be hel...

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Bibliographic Details
Main Authors: Baiba Svalbe, Baiba Zvejniece, Gundega Stelfa, Karlis Vilks, Edijs Vavers, José Miguel Vela, Maija Dambrova, Liga Zvejniece
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Biomedicines
Subjects:
Online Access:https://www.mdpi.com/2227-9059/10/7/1572