Protein Kinase CK2 Controls Ca<sub>V</sub>2.1-Dependent Calcium Currents and Insulin Release in Pancreatic β-cells

Protein Kinase CK2 Controls Ca<sub>V</sub>2.1-Dependent Calcium Currents and Insulin Release in Pancreatic β-cells

The regulation of insulin biosynthesis and secretion in pancreatic β-cells is essential for glucose homeostasis in humans. Previous findings point to the highly conserved, ubiquitously expressed serine/threonine kinase CK2 as having a negative regulatory impact on this regulation. In the cell cultur...

Full description

Bibliographic Details
Main Authors: Rebecca Scheuer, Stephan Ernst Philipp, Alexander Becker, Lisa Nalbach, Emmanuel Ampofo, Mathias Montenarh, Claudia Götz
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:International Journal of Molecular Sciences
Subjects:
CK2
INS-1
CX-4945
Ca<sub>V</sub>2.1
insulin secretion
Online Access:https://www.mdpi.com/1422-0067/21/13/4668

Internet

https://www.mdpi.com/1422-0067/21/13/4668

Similar Items