CRISPR/Cas13a Powered Portable Electrochemiluminescence Chip for Ultrasensitive and Specific MiRNA Detection

CRISPR/Cas13a Powered Portable Electrochemiluminescence Chip for Ultrasensitive and Specific MiRNA Detection

Abstract MicroRNAs (miRNAs) have been widely investigated as potential biomarkers for early clinical diagnosis of cancer. Developing an miRNA detection platform with high specificity, sensitivity, and exploitability is always necessary. Electrochemiluminescence (ECL) is an electrogenerated chemilumi...

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Bibliographic Details
Main Authors: Ting Zhou, Ru Huang, Mengqi Huang, Jinjin Shen, Yuanyue Shan, Da Xing
Format: Article
Language:English
Published: Wiley 2020-07-01
Series:Advanced Science
Subjects:
CRISPR/Cas13a
light‐switch [Ru(phen)2dppz]2+
miRNA detection
pBPE‐ECL
trans‐cleavage activity
Online Access:https://doi.org/10.1002/advs.201903661

Internet

https://doi.org/10.1002/advs.201903661

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