Single-cycle adenovirus vectors in the current vaccine landscape

Introduction: Traditional inactivated and protein vaccines generate strong antibodies, but struggle to generate T cell responses. Attenuated pathogen vaccines generate both, but risk causing the disease they aim to prevent. Newer gene-based vaccines drive both responses and avoid the risk of infecti...

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Bibliographic Details
Main Author: Michael Barry
Format: Article
Language:English
Published: Taylor & Francis Group 2018-02-01
Series:Expert Review of Vaccines
Subjects:
Online Access:http://dx.doi.org/10.1080/14760584.2018.1419067