The vertebrate- and testis- specific transmembrane protein C11ORF94 plays a critical role in sperm-oocyte membrane binding

The vertebrate- and testis- specific transmembrane protein C11ORF94 plays a critical role in sperm-oocyte membrane binding

Abstract Sperm-oocyte membrane fusion is necessary for mammalian fertilization. The factors that determine the fusion of sperm with oocytes are largely unknown. So far, spermatozoon factor IZUMO1 and the IZUMO1 counter-receptor JUNO on the oocyte membrane has been identified as a protein requiring f...

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Bibliographic Details
Main Authors: Hongying Hao, Baolu Shi, Jiacheng Zhang, Ao Dai, Wenhao Li, Haidi Chen, Wenya Ji, Chenjia Gong, Chang Zhang, Jing Li, Li Chen, Bin Yao, Peng Hu, Hao Yang, Juergen Brosius, Shanshan Lai, Qinghua Shi, Cheng Deng
Format: Article
Language:English
Published: Springer 2022-09-01
Series:Molecular Biomedicine
Subjects:
C11orf94
Male fertility
Fertilization
Sperm-oocyte binding
Sperm-oocyte fusion
Horizontal gene transfer
Online Access:https://doi.org/10.1186/s43556-022-00092-1

Internet

https://doi.org/10.1186/s43556-022-00092-1

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