Anti-inflammatory effects of minocycline are mediated by retinoid signaling

Anti-inflammatory effects of minocycline are mediated by retinoid signaling

Abstract Background Minocycline is a lipophilic tetracycline of increasing appeal in neuroscience as it inhibits microglial activation, a mechanism involved in numerous neuropsychiatric disorders. Own data point towards retinoid-mediated effects of minocycline in murine brain and skin, and towards a...

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Bibliographic Details
Main Authors: Vera Clemens, Francesca Regen, Nathalie Le Bret, Isabella Heuser, Julian Hellmann-Regen
Format: Article
Language:English
Published: BMC 2018-09-01
Series:BMC Neuroscience
Subjects:
Minocycline
Retinoic acid
Neuroinflammation
Microglia
Cytokines
Online Access:http://link.springer.com/article/10.1186/s12868-018-0460-x

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http://link.springer.com/article/10.1186/s12868-018-0460-x

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