Soy isoflavones induces mitophagy to inhibit the progression of osteosarcoma by blocking the AKT/mTOR signaling pathway

Soy isoflavones induces mitophagy to inhibit the progression of osteosarcoma by blocking the AKT/mTOR signaling pathway

Abstract Background Soy isoflavones (SI) is a natural bioactive substance exhibiting beneficial effects on human health. This study aims to elucidate the therapeutic potential of SI in the treatment of osteosarcoma (OS) and to investigate the underlying mechanisms, particularly focusing on mitophagy...

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Bibliographic Details
Main Authors: Ziang Zheng, Xinghan Zhao, Bo Yuan, Shan Jiang, Rushan Yan, Xiaowei Dong, Qijun Yao, Haidong Liang
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Molecular Medicine
Subjects:
Osteosarcoma
Soy isoflavones
Mitophagy
Autophagy
AKT/mTOR pathway
Online Access:https://doi.org/10.1186/s10020-024-00778-y

Internet

https://doi.org/10.1186/s10020-024-00778-y

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