Preparation of antibacterial and osteoconductive 3D-printed PLGA/Cu(I)@ZIF-8 nanocomposite scaffolds for infected bone repair

Preparation of antibacterial and osteoconductive 3D-printed PLGA/Cu(I)@ZIF-8 nanocomposite scaffolds for infected bone repair

Abstract Background The repair of large bone defects is a great challenge in clinical practice. In this study, copper-loaded-ZIF-8 nanoparticles and poly (lactide-co-glycolide) (PLGA) were combined to fabricate porous PLGA/Cu(I)@ZIF-8 scaffolds using three-dimensional printing technology for infecte...

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Bibliographic Details
Main Authors: Fei Zou, Jianyuan Jiang, Feizhou Lv, Xinlei Xia, Xiaosheng Ma
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Journal of Nanobiotechnology
Subjects:
ZIF-8
Three-dimensional printing
Biomaterial scaffold
Antibacterial property
Osteoblastic differentiation
Online Access:http://link.springer.com/article/10.1186/s12951-020-00594-6

Internet

http://link.springer.com/article/10.1186/s12951-020-00594-6

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