Enhancing Stability of Camelid and Shark Single Domain Antibodies: An Overview

Enhancing Stability of Camelid and Shark Single Domain Antibodies: An Overview

Single domain antibodies (sdAbs) are gaining a reputation as superior recognition elements as they combine the advantages of the specificity and affinity found in conventional antibodies with high stability and solubility. Melting temperatures (Tms) of sdAbs cover a wide range from below 50 to over...

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Bibliographic Details
Main Authors: Ellen R. Goldman, Jinny L. Liu, Dan Zabetakis, George P. Anderson
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-07-01
Series:Frontiers in Immunology
Subjects:
single domain antibody
camelid
shark
protein engineering
stability
melting temperature
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.00865/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.00865/full

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