The transcription factor Spalt and human homologue SALL4 induce cell invasion via the dMyc-JNK pathway in Drosophila

The transcription factor Spalt and human homologue SALL4 induce cell invasion via the dMyc-JNK pathway in Drosophila

Cancer cell metastasis is a leading cause of mortality in cancer patients. Therefore, revealing the molecular mechanism of cancer cell invasion is of great significance for the treatment of cancer. In human patients, the hyperactivity of transcription factor Spalt-like 4 (SALL4) is sufficient to ind...

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Bibliographic Details
Main Authors: Jie Sun, Junzheng Zhang, Dan Wang, Jie Shen
Format: Article
Language:English
Published: The Company of Biologists 2020-03-01
Series:Biology Open
Subjects:
spalt
sall4
jnk pathway
dmyc
cell invasion
Online Access:http://bio.biologists.org/content/9/3/bio048850

Internet

http://bio.biologists.org/content/9/3/bio048850

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