Bacterial DNA amplifies neutrophilic inflammation in IL-17-exposed airways

Background Neutrophilic asthma (NA) is associated with increased airway interleukin (IL)-17 and abnormal bacterial community such as dominance of nontypeable Haemophilus influenzae (NTHi), particularly during asthma exacerbations. Bacteria release various products including DNA, but whether they coo...

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Bibliographic Details
Main Authors: Nastaran Mues, Richard J. Martin, Rafeul Alam, Niccolette Schaunaman, Kris Genelyn Dimasuay, Christena Kolakowski, Clyde J. Wright, Lijun Zheng, Hong Wei Chu
Format: Article
Language:English
Published: European Respiratory Society 2023-01-01
Series:ERJ Open Research
Online Access:http://openres.ersjournals.com/content/9/1/00474-2022.full