Relationship between concavity of the flow-volume loop and small airway measures in smokers with normal spirometry

Abstract Background There is increasing evidence of small airway abnormalities in smokers despite normal spirometry. The concavity in the descending limb of the maximum expiratory flow curve (MEFV) is a recognised feature of obstruction and can provide information beyond FEV1, and potentially early...

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Bibliographic Details
Main Authors: Hooria Alowiwi, Stella Watson, Kanika Jetmalani, Cindy Thamrin, David P. Johns, E. Haydn Walters, Gregory G. King
Format: Article
Language:English
Published: BMC 2022-05-01
Series:BMC Pulmonary Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12890-022-01998-w