HES1 promotes aerobic glycolysis and cancer progression of colorectal cancer via IGF2BP2-mediated GLUT1 m6A modification

HES1 promotes aerobic glycolysis and cancer progression of colorectal cancer via IGF2BP2-mediated GLUT1 m6A modification

Abstract Aerobic glycolysis has been shown to play a key role in tumor cell proliferation and metastasis. However, how it is directly regulated is largely unknown. Here, we found that HES1 expression was significantly higher in CRC tissues than that in adjacent normal tissues. Moreover, high HES1 ex...

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Bibliographic Details
Main Authors: Jiayu Wang, Mengxin Zhu, Jinghan Zhu, Juntao Li, Xingchao Zhu, Kun Wang, Kanger Shen, Kexi Yang, Xiangyu Ni, Xin Liu, Guangbo Zhang, Qinhua Xi, Tongguo Shi, Weichang Chen
Format: Article
Language:English
Published: Nature Publishing Group 2023-11-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-023-01707-4

Internet

https://doi.org/10.1038/s41420-023-01707-4

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