Synthesis, Cytotoxicity and Anti-Proliferative Activity against AGS Cells of New 3(2<i>H</i>)-Pyridazinone Derivatives Endowed with a Piperazinyl Linker
Novel twenty-three 3(2<i>H</i>)-pyridazinone derivatives were designed and synthesized based on the chemical requirements related to the anti-proliferative effects previously demonstrated within this scaffold. The introduction of a piperazinyl linker between the pyridazinone nucleus and...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-02-01
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Series: | Pharmaceuticals |
Subjects: | |
Online Access: | https://www.mdpi.com/1424-8247/14/3/183 |