Colorectal Cancer Is Borrowing Blueprints from Intestinal Ontogenesis

Colorectal Cancer Is Borrowing Blueprints from Intestinal Ontogenesis

Colorectal tumors are heterogenous cellular systems harboring small populations of self-renewing and highly tumorigenic cancer stem cells (CSCs). Understanding the mechanisms fundamental to the emergence of CSCs and colorectal tumor initiation is crucial for developing effective therapeutic strategi...

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Bibliographic Details
Main Authors: Jacob L. Billingsley, Veronika Yevdokimova, Kristina Ayoub, Yannick D. Benoit
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Cancers
Subjects:
colorectal cancer
cancer stem cells
oncogenic reprogramming
Sox9
chemical genomics
differentiation therapy
Online Access:https://www.mdpi.com/2072-6694/15/20/4928

Internet

https://www.mdpi.com/2072-6694/15/20/4928

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