Nanoparticle-based immunotherapy of pancreatic cancer

Nanoparticle-based immunotherapy of pancreatic cancer

Pancreatic cancer (PC) has a complex and unique tumor microenvironment (TME). Due to the physical barrier formed by the desmoplastic stroma, the delivery of drugs to the tumor tissue is limited. The TME also contributes to resistance to various immunotherapies such as cancer vaccines, chimeric antig...

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Bibliographic Details
Main Authors: Gaetan Aime Noubissi Nzeteu, Bernhard F. Gibbs, Nika Kotnik, Achim Troja, Maximilian Bockhorn, N. Helge Meyer
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Molecular Biosciences
Subjects:
pancreatic cancer
tumor microenvironment
nanoparticles
immune checkpoint inhibitors
immunotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2022.948898/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2022.948898/full

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