Insights to the Structural Basis for the Stereospecificity of the <i>Escherichia coli</i> Phytase, AppA

Insights to the Structural Basis for the Stereospecificity of the <i>Escherichia coli</i> Phytase, AppA

AppA, the <i>Escherichia coli</i> periplasmic phytase of clade 2 of the histidine phosphatase (HP2) family, has been well-characterized and successfully engineered for use as an animal feed supplement. AppA is a 1D-6-phytase and highly stereospecific but transiently accumulates 1D-<i&...

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Bibliographic Details
Main Authors: Isabella M. Acquistapace, Emma J. Thompson, Imke Kühn, Mike R. Bedford, Charles A. Brearley, Andrew M. Hemmings
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:International Journal of Molecular Sciences
Subjects:
phytase
AppA
enzymology
catalytic mechanism
stereospecificity
enzyme structure
Online Access:https://www.mdpi.com/1422-0067/23/11/6346

Internet

https://www.mdpi.com/1422-0067/23/11/6346

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