A New Method for Identifying Essential Proteins Based on Network Topology Properties and Protein Complexes.

Essential proteins are indispensable to the viability and reproduction of an organism. The identification of essential proteins is necessary not only for understanding the molecular mechanisms of cellular life but also for disease diagnosis, medical treatments and drug design. Many computational met...

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Bibliographic Details
Main Authors: Chao Qin, Yongqi Sun, Yadong Dong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4987049?pdf=render