Identification of hub genes and transcription factor-miRNA-mRNA pathways in mice and human renal ischemia-reperfusion injury

Identification of hub genes and transcription factor-miRNA-mRNA pathways in mice and human renal ischemia-reperfusion injury

Background Renal ischemia-reperfusion injury (IRI) is a disease with high incidence rate in kidney related surgery. Micro RNA (miRNA) and transcription factors (TFs) are widely involved in the process of renal IRI through regulation of their target genes. However, the regulatory relationships and fu...

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Bibliographic Details
Main Authors: Peng Ke, Lin Qian, Yi Zhou, Liu Feng, Zhentao Zhang, Chengjie Zheng, Mengnan Chen, Xinlei Huang, Xiaodan Wu
Format: Article
Language:English
Published: PeerJ Inc. 2021-10-01
Series:PeerJ
Subjects:
Bioinformatics analysis
Hub genes
Ischemia-reperfusion injury
Renal injury
Transcription factor
Online Access:https://peerj.com/articles/12375.pdf

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https://peerj.com/articles/12375.pdf

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