miR-21 promotes the fibrotic properties in oral mucosa through targeting PDCD4

Background/purpose: Oral submucous fibrosis (OSF) has been regarded as a premalignant disorder of oral cancer, and myofibroblasts are the main cells that are responsible for pathological fibrosis. Hence, elucidation of the molecular mechanism underlying myofibroblast activation is important to treat...

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Bibliographic Details
Main Authors: Yi-Wen Liao, Lo-Lin Tsai, Yu-Hsien Lee, Pei-Ling Hsieh, Cheng-Chia Yu, Ming-Yi Lu
Format: Article
Language:English
Published: Elsevier 2022-04-01
Series:Journal of Dental Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1991790221002130