miR-21 promotes the fibrotic properties in oral mucosa through targeting PDCD4

Background/purpose: Oral submucous fibrosis (OSF) has been regarded as a premalignant disorder of oral cancer, and myofibroblasts are the main cells that are responsible for pathological fibrosis. Hence, elucidation of the molecular mechanism underlying myofibroblast activation is important to treat...

Полное описание

Библиографические подробности
Главные авторы: Yi-Wen Liao, Lo-Lin Tsai, Yu-Hsien Lee, Pei-Ling Hsieh, Cheng-Chia Yu, Ming-Yi Lu
Формат: Статья
Язык:English
Опубликовано: Elsevier 2022-04-01
Серии:Journal of Dental Sciences
Предметы:
Online-ссылка:http://www.sciencedirect.com/science/article/pii/S1991790221002130