Osteoarthritis-Induced Metabolic Alterations of Human Hip Chondrocytes

Osteoarthritis-Induced Metabolic Alterations of Human Hip Chondrocytes

Osteoarthritis (OA) alters chondrocyte metabolism and mitochondrial biology. We explored whether OA and non-OA chondrocytes show persistent differences in metabolism and mitochondrial function and different responsiveness to cytokines and cAMP modulators. Hip chondrocytes from patients with OA or fe...

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Bibliographic Details
Main Authors: Annett Eitner, Simon Sparing, Felix C. Kohler, Sylvia Müller, Gunther O. Hofmann, Thomas Kamradt, Hans-Georg Schaible, Matthias Aurich
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Biomedicines
Subjects:
osteoarthritis
metabolic alterations
chondrocytes
oxygen consumption rate
mitochondrial ATP production
opioid peptides
Online Access:https://www.mdpi.com/2227-9059/10/6/1349

Internet

https://www.mdpi.com/2227-9059/10/6/1349

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