Cytotoxic 1,3-Thiazole and 1,2,4-Thiadiazole Alkaloids from Penicillium oxalicum: Structural Elucidation and Total Synthesis

Cytotoxic 1,3-Thiazole and 1,2,4-Thiadiazole Alkaloids from Penicillium oxalicum: Structural Elucidation and Total Synthesis

Two new thiazole and thiadiazole alkaloids, penicilliumthiamine A and B (2 and 3), were isolated from the culture broth of Penicillium oxalicum, a fungus found in Acrida cinerea. Their structures were elucidated mainly by spectroscopic analysis, total synthesis and X-ray crystallographic analysis. B...

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Bibliographic Details
Main Authors: Zheng Yang, Nianyu Huang, Bang Xu, Wenfeng Huang, Tianpeng Xie, Fan Cheng, Kun Zou
Format: Article
Language:English
Published: MDPI AG 2016-02-01
Series:Molecules
Subjects:
Penicillium oxalicum
alkaloids
total synthesis
structure elucidation
cytotoxicity
Online Access:http://www.mdpi.com/1420-3049/21/3/232

Internet

http://www.mdpi.com/1420-3049/21/3/232

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