Dietary oxidized n-3 PUFA induce oxidative stress and inflammation: role of intestinal absorption of 4-HHE and reactivity in intestinal cells

Dietary oxidized n-3 PUFA induce oxidative stress and inflammation: role of intestinal absorption of 4-HHE and reactivity in intestinal cells

Dietary intake of long-chain n-3 PUFA is now widely advised for public health and in medical practice. However, PUFA are highly prone to oxidation, producing potentially deleterious 4-hydroxy-2-alkenals. Even so, the impact of consuming oxidized n-3 PUFA on metabolic oxidative stress and inflammatio...

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Bibliographic Details
Main Authors: Manar Awada, Christophe O. Soulage, Anne Meynier, Cyrille Debard, Pascale Plaisancié, Bérengère Benoit, Grégory Picard, Emmanuelle Loizon, Marie-Agnès Chauvin, Monique Estienne, Noël Peretti, Michel Guichardant, Michel Lagarde, Claude Genot, Marie-Caroline Michalski
Format: Article
Language:English
Published: Elsevier 2012-10-01
Series:Journal of Lipid Research
Subjects:
nutrition
polyunsaturated fatty acids
lipid peroxidation
4-hydroxy-2-alkenals
intestine
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520431840

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http://www.sciencedirect.com/science/article/pii/S0022227520431840

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